Expression Profiling of Acetaminophen Liver Toxicity in Mice Using Microarray Technology

Drug-induced hepatotoxicity causes significant morbidity and mortality and is a major concern in drug development. This is due, in large part, to insufficient knowledge of the mechanism(s) of drug-induced liver injury. In order to address this problem, we have evaluated the modulation of gene expres...

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Veröffentlicht in:Biochemical and biophysical research communications 2001-03, Vol.282 (1), p.321-328
Hauptverfasser: Reilly, Timothy P., Bourdi, Mohammed, Brady, John N., Pise-Masison, Cynthia A., Radonovich, Michael F., George, John W., Pohl, Lance R.
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Sprache:eng
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