Interleukin-18 Induces Activation and Association of p56lck and MAPK in a Murine TH1 Clone

Interleukin-18 (IL-18) was identified as an inducer of interferon-γ (IFN-γ) production by stimulated T cells. In this study, we used an ovalbumin-responsive murine Th1 clone (OVA#4), in which DNA synthesis was reportedly enhanced after IL-18 treatment in the presence of a non-mitogenic TCR/CD3 stimu...

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Veröffentlicht in:Biochemical and biophysical research communications 1997-08, Vol.237 (1), p.126-130
Hauptverfasser: Tsuji-Takayama, Kazue, Matsumoto, Shuji, Koide, Kazuhiro, Takeuchi, Makoto, Ikeda, Masao, Ohta, Tsunetaka, Kurimoto, Masashi
Format: Artikel
Sprache:eng
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