The EGF Receptor Binding of Recombinant Heregulinβ1/EGF Hybrids Is Blocked by Heregulin Residue Glutamate 195

Defined sequences from the EGF-like domain of human heregulin-β1 (HRGβ1) were recombined with a synthetic gene for human epidermal growth factor (hEGF) in an attempt to locate receptor-specific determinants within the HRGβ1 molecule that blocks its inappropriate association with the EGF receptor (EG...

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Veröffentlicht in:Biochemical and biophysical research communications 1996-12, Vol.229 (3), p.882-886
Hauptverfasser: Chau, B.Nelson, Nandagopal, Krishnadas, Niyogi, Salil K., Campion, Stephen R.
Format: Artikel
Sprache:eng
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