N23K, A Gene Transiently Up-Regulated during Neural Differentiation, Encodes a Precursor Protein for a Newly Identified Neuropeptide Nociceptin

We used a subtraction cloning approach to isolate a cDNA of N23K, whose mRNA and protein are transiently up-regulated in mouse NS20Y cells undergoing neurite outgrowth induced by treatment of dibutyryl cyclic AMP. N23K encodes a precursor protein for a newly discovered rat neuropeptide nociceptin. A...

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Veröffentlicht in:	Biochemical and biophysical research communications 1995-12, Vol.217 (2), p.539-545
Hauptverfasser:	Saito, Y., Maruyama, K., Saido, T.C., Kawashima, S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Base Sequence Blotting, Western Cloning, Molecular DNA, Complementary - genetics Gene Expression Regulation, Developmental Genes Mice Molecular Sequence Data Neurons - cytology Neuropeptides - genetics Nociceptin Opioid Peptides - genetics Repetitive Sequences, Nucleic Acid RNA, Messenger - genetics Sequence Alignment Sequence Homology, Amino Acid Tissue Distribution Up-Regulation
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