β1-6 Branching of N-Linked Carbohydrate Is Associated with K-ras Mutation in Human Colon Carcinoma Cell Lines

Here the K-ras genotypes of nine colon carcinoma cell lines are compared to the protein glycosylation patterns found in these cells. By a variety of methodologies utilizing lectins to probe carbohydrate structure, we find evidence that five out of six cell lines having K-ras mutations have elevated...

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Veröffentlicht in:Biochemical and biophysical research communications 1995-07, Vol.212 (3), p.758-766
Hauptverfasser: Wojciechowicz, D.C., Park, P.Y., Paty, P.B.
Format: Artikel
Sprache:eng
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