Expression of Cytochrome P450 mRNAs in the Colon and the Rectum in Normal Human Subjects

The expression of mRNA for three isozymes of cytochrome P450, CYP1A1, 1A2 and 3A3, was examined in biopsied samples of colon and rectum from five healthy subjects. Using RT-PCR, it was possible to detect the three CYP mRNA species at both sites in all samples examined. The expression of each CYP mRN...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Biochemical and biophysical research communications 1995-05, Vol.210 (2), p.350-355
Hauptverfasser:	Mercurio, M.G., Shiff, S.J., Galbraith, R.A., Sassa, S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Base Sequence Colon - enzymology Cytochrome P-450 CYP3A Cytochrome P-450 Enzyme System - biosynthesis Cytochrome P-450 Enzyme System - genetics DNA Primers Electrophoresis, Polyacrylamide Gel Female Humans Isoenzymes - biosynthesis Isoenzymes - genetics Male Middle Aged Molecular Sequence Data Polymerase Chain Reaction Rectum - enzymology Reference Values RNA, Messenger - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!