Epidermal Growth Factor Triggers the Translocation of Insulin-Responsive Glucose Transporter (GLUT4)

In a novel cell line we developed for direct, sensitive detection of insulin-responsive glucose transporter (GLUT4) on the cell surface, we considered that insulin-activated phosphatidylinositol 3-kinase (PI 3-kinase) may be involved in the signaling pathway of insulin-stimulated GLUT4 translocation...

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Veröffentlicht in:	Biochemical and biophysical research communications 1994-11, Vol.205 (1), p.857-863
Hauptverfasser:	Ishii, K., Kamohara, S., Hayashi, H., Todaka, M., Kanai, F., Imanaka, T., Ebina, Y.
Format:	Artikel
Sprache:	eng
Schlagworte:	Androstadienes - pharmacology Animals Biological Transport CHO Cells Cricetinae Enzyme Activation Epidermal Growth Factor - physiology Glucose - metabolism Glucose Transporter Type 4 Insulin - pharmacology Monosaccharide Transport Proteins - metabolism Muscle Proteins Phorbol 12,13-Dibutyrate - pharmacology Phosphatidylinositol 3-Kinases Phosphotransferases (Alcohol Group Acceptor) - antagonists & inhibitors Phosphotransferases (Alcohol Group Acceptor) - metabolism
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