Translocation of Retinoblastoma Protein Associated with Tumor Cell Growth Inhibition

Immunocytochemistry revealed an association between growth inhibition and a translocation of retinoblastoma protein (pRB) to the nucleoli of U-2 osteosarcoma cells inhibited in their growth by the negative growth factor NCPI (natural cell proliferation inhibitor). Similar phenomenon was demonstrated...

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Veröffentlicht in:	Biochemical and biophysical research communications 1993-05, Vol.192 (3), p.1139-1146
Hauptverfasser:	Rogalsky, V., Todorov, G., Moran, D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Blotting, Western Cell Differentiation - drug effects Cell Division - drug effects Cell Nucleolus - metabolism Cell physiology Cell transformation and carcinogenesis. Action of oncogenes and antioncogenes DNA Replication - drug effects DNA, Neoplasm - biosynthesis Fundamental and applied biological sciences. Psychology Humans Immunoenzyme Techniques Immunohistochemistry Leukemia, Monocytic, Acute Molecular and cellular biology Molecular Weight Osteosarcoma Retinoblastoma Protein - analysis Retinoblastoma Protein - isolation & purification Retinoblastoma Protein - metabolism Tetradecanoylphorbol Acetate - pharmacology Tumor Cells, Cultured
Online-Zugang:	Volltext
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