Fibroblast Growth Factor-Mediated Growth Regulation and Receptor Expression in Embryonal Carcinoma and Embryonic Stem Cells and Human Germ Cell Tumors

FGFs have been implicated in the induction of mesoderm in amphibian development and are present in the mouse embryo at stages that would be appropriate for a similar function in mammals. Primitive ectoderm would then he the target tissue. We have now characterized changes in the expression of recept...

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Veröffentlicht in:	Biochemical and biophysical research communications 1993-02, Vol.191 (1), p.188-195
Hauptverfasser:	Mummery, C.L., Vanrooyen, M., Bracke, M., Vandeneijndenvanraaij, J., Vanzoelen, E.J., Alitalo, K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Blotting, Northern Bucladesine - pharmacology Cell Differentiation - drug effects Cell Differentiation - physiology Cell Division - drug effects Cell Line Cell physiology Culture Media, Conditioned Down-Regulation - drug effects Embryo, Mammalian Fibroblast Growth Factor 1 - pharmacology Fibroblast Growth Factor 2 - pharmacology Fibroblast Growth Factor 4 Fibroblast Growth Factors - pharmacology Fundamental and applied biological sciences. Psychology Laminin Liver - cytology Mice Molecular and cellular biology Poly A - genetics Poly A - isolation & purification Proto-Oncogene Proteins - pharmacology Rats Rats, Inbred BUF Receptors, Fibroblast Growth Factor - drug effects Receptors, Fibroblast Growth Factor - genetics Receptors, Fibroblast Growth Factor - metabolism Responses to growth factors, tumor promotors, other factors RNA - genetics RNA - isolation & purification RNA, Messenger - isolation & purification RNA, Messenger - metabolism Stem Cells - cytology Stem Cells - drug effects Stem Cells - metabolism Teratoma Transcription, Genetic Tretinoin - pharmacology Tumor Cells, Cultured
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