Effect of Autophosphorylation on the Catalytic and Regulatory Properties of Protein Tyrosine Kinase Src

The function of autophosphorylation in Src family protein tyrosine kinases is not fully understood. In this paper we compared the catalytic and ligand-binding properties of autophosphorylated and nonautophosphorylated (control) Src. The following are the main differences we found. First, while both...

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