In silico screening of alkaloids as potential inhibitors of HER2 protein for breast cancer treatment

In breast cancers, the expression of the human epidermal growth factor‐2 (HER2) receptor protein target is overexpressed, which plays a critical role in the development of breast cancer. The HER2 inhibitor neratinib, which is currently on the market, specifically targets the ATP‐binding site of the...

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Veröffentlicht in:	Vietnam journal of chemistry 2023-06, Vol.61 (3), p.308-317
Hauptverfasser:	Tung, Bui Thanh, Son, Nguyen Nhu, Kim, Nguyen Bao, Khanh, Do Thi Hong, Minh, Phan Hong
Format:	Artikel
Sprache:	eng
Schlagworte:	Alkaloids breast cancer Human Epidermal Growth Factor Receptor‐2 (HER2) Lipinski's rule molecular docking
Online-Zugang:	Volltext
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