Vitamin B complex blocks the dust fall PM 2 .5 -induced acute lung injury through DNA methylation in rats

This study aimed to explore whether vitamin B complex (folic acid, B , and B ) could avert DNA methylation changes associated with inflammation induced by acute PM exposure. Sprague-Dawley rats were administered by gavage with different concentrations of vitamin B complex once a day for 28 days, and...

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Veröffentlicht in:	Environmental toxicology 2023-02, Vol.38 (2), p.403-414
Hauptverfasser:	Bai, Jun, Tang, Lanlan, Luo, Yajun, Han, Zhixia, Li, Chenwen, Sun, Yaochuan, Sun, Qian, Lu, Ji, Qiu, Hao, Zhao, Zhenhu, Huo, Tingting, Xiong, Wei, Zhang, Qingbi
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Lung Injury - chemically induced Acute Lung Injury - genetics Animals DNA Methylation Dust Folic Acid Inflammation - pathology Interleukin-4 - genetics Lung - pathology Lung Injury - chemically induced Lung Injury - genetics Particulate Matter - toxicity Rats Rats, Sprague-Dawley S-Adenosylmethionine - toxicity Vitamin B Complex - pharmacology
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