17β-Trenbolone exposure programs metabolic dysfunction in larval medaka

Here, we used physiological and transcriptomic analyses to evaluate the effects of 17β‐trenbolone (TB) on metabolism during the early life stage of medaka (Oryzias latipes). In the physiological experiments, sex reversal rates increased continuously in proportion to TB concentrations (2–100 ng/L), a...

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Veröffentlicht in:	Environmental toxicology 2016-11, Vol.31 (11), p.1539-1551
Hauptverfasser:	Mizukami-Murata, Satomi, Kishi-Kadota, Katsuyuki, Nishida, Takashi
Format:	Artikel
Sprache:	eng
Schlagworte:	17β-trenbolone Animals body mass index cholesterol synthesis Female Fertility - drug effects Gene Expression Regulation - drug effects Larva - drug effects Larva - metabolism larval medaka Lipid Metabolism - drug effects Male obesity Oryzias - metabolism Polyketides - metabolism Terpenes - metabolism Transcriptome Trenbolone Acetate - toxicity
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