Fetal anemia following maternal exposure to 5-fluorouracil in the rat

Previous studies from our laboratory have shown that maternal 5‐fluorouracil (5‐FU) exposure on day 14 of gestation (GD14) in the rat results in dose‐dependent retardation of both cell cycle progression and growth of embryonic liver. At this developmental stage, hepatic erythropoiesis is the primary...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Teratology (Philadelphia) 1994-04, Vol.49 (4), p.311-319
Hauptverfasser:	Shuey, Dana L., Zucker, Robert M., Elstein, Kenneth H., Rogers, John M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Anemia - chemically induced Anemia - embryology Animals Biological and medical sciences Drug toxicity and drugs side effects treatment Embryonic and Fetal Development - drug effects Erythropoiesis - drug effects Female Fetal Diseases - chemically induced Fluorouracil - toxicity Hematopoiesis, Extramedullary - drug effects Liver - drug effects Liver - pathology Medical sciences Pharmacology. Drug treatments Pregnancy Rats Rats, Sprague-Dawley Teratogens - toxicity Toxicity: blood
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!