Non-confirmation of thalidomide induced teratogenesis in rats and mice

It has been reported that thalidomide, dissolved in a 1:3 mixture of Tween 20 and physiological saline and administered intraperitoneally to pregnant mice and rats induces a variety of malformations, including limb deformities, characteristic of the primate syndrome. The studies reported herein atte...

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Veröffentlicht in:	Teratology (Philadelphia) 1977-12, Vol.16 (3), p.333-335
Hauptverfasser:	Scott, W. J., Fradkin, R., Wilson, J. G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Abnormalities, Drug-Induced - embryology Animals Female Fetal Resorption - chemically induced Mice - embryology Pharmaceutical Vehicles Polysorbates - toxicity Pregnancy Rats - embryology Thalidomide - administration & dosage
Online-Zugang:	Volltext
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