Multifunctional Carbon Dots Derived from Human Hair for Fast Healing Wounds Together with Oleogels

In the complex process of wound healing, oleogels (OG) are suitable as the primary component of dressing materials, but they cannot meet the diverse requirements at different healing stages. In this study, a new kind of carbon dots (CrCi‐CDs) prepared by carbonizing human hair, exhibits excellent he...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Small structures 2024-10
Hauptverfasser: Shi, Xiaofeng, Ma, Qianli, Jia, Xinlin, Wu, Zhaofan, Yu, Chaohong, Gao, Tian, Xu, Wei, Sun, Zhaonan, Zhang, Jingwei, Xiong, Huanming, Mao, Yuanqing
Format: Artikel
Sprache:eng
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue
container_start_page
container_title Small structures
container_volume
creator Shi, Xiaofeng
Ma, Qianli
Jia, Xinlin
Wu, Zhaofan
Yu, Chaohong
Gao, Tian
Xu, Wei
Sun, Zhaonan
Zhang, Jingwei
Xiong, Huanming
Mao, Yuanqing
description In the complex process of wound healing, oleogels (OG) are suitable as the primary component of dressing materials, but they cannot meet the diverse requirements at different healing stages. In this study, a new kind of carbon dots (CrCi‐CDs) prepared by carbonizing human hair, exhibits excellent hemostatic, antibacterial, anti‐inflammatory, and pro‐angiogenic properties and thus supports the various stages of wound healing effectively. Such CrCi‐CDs are incorporated into OG to produce a CrCi‐CD/OG composite material with enhanced multifunctional capabilities, significantly outperforming OG alone. Various experiments in vitro and in vivo confirm that the CrCi‐CDs/OG can rapidly achieve hemostasis at the initial stage of wound formation, subsequently inhibit bacterial proliferation and biofilm formation, improve the complex microenvironment surrounding the wound, and promote neovascularization, ultimately accelerating the wound repair.
doi_str_mv 10.1002/sstr.202400435
format Article
fullrecord <record><control><sourceid>crossref</sourceid><recordid>TN_cdi_crossref_primary_10_1002_sstr_202400435</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>10_1002_sstr_202400435</sourcerecordid><originalsourceid>FETCH-LOGICAL-c124t-3b0f2406de3e18fa20c01b272ab734f236f43d9c5f66545c877898690517589d3</originalsourceid><addsrcrecordid>eNpNkE1LAzEYhIMoWGqvnvMHtr75zh6lta5Q6aXiccnuJm1kdyNJVvHf26KIp5k5zDA8CN0SWBIAepdSjksKlANwJi7QjEqtCw6SXv7z12iR0hucCoIQVaoZap6nPns3jW32YTQ9XpnYhBGvQ054baP_sB12MQy4mgYz4sr4iF2IeGNSxpU1vR8P-DVMY5fwPhxsPtqIP30-4l1vT7lPN-jKmT7Zxa_O0cvmYb-qiu3u8Wl1vy1aQnkuWAPudF92llminaHQAmmooqZRjDvKpOOsK1vhpBRctFopXWpZgiBK6LJjc7T82W1jSClaV79HP5j4VROoz5DqM6T6DxL7Bvt0WoA</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>Multifunctional Carbon Dots Derived from Human Hair for Fast Healing Wounds Together with Oleogels</title><source>Wiley Online Library - AutoHoldings Journals</source><source>DOAJ Directory of Open Access Journals</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>Wiley Online Library (Open Access Collection)</source><creator>Shi, Xiaofeng ; Ma, Qianli ; Jia, Xinlin ; Wu, Zhaofan ; Yu, Chaohong ; Gao, Tian ; Xu, Wei ; Sun, Zhaonan ; Zhang, Jingwei ; Xiong, Huanming ; Mao, Yuanqing</creator><creatorcontrib>Shi, Xiaofeng ; Ma, Qianli ; Jia, Xinlin ; Wu, Zhaofan ; Yu, Chaohong ; Gao, Tian ; Xu, Wei ; Sun, Zhaonan ; Zhang, Jingwei ; Xiong, Huanming ; Mao, Yuanqing</creatorcontrib><description>In the complex process of wound healing, oleogels (OG) are suitable as the primary component of dressing materials, but they cannot meet the diverse requirements at different healing stages. In this study, a new kind of carbon dots (CrCi‐CDs) prepared by carbonizing human hair, exhibits excellent hemostatic, antibacterial, anti‐inflammatory, and pro‐angiogenic properties and thus supports the various stages of wound healing effectively. Such CrCi‐CDs are incorporated into OG to produce a CrCi‐CD/OG composite material with enhanced multifunctional capabilities, significantly outperforming OG alone. Various experiments in vitro and in vivo confirm that the CrCi‐CDs/OG can rapidly achieve hemostasis at the initial stage of wound formation, subsequently inhibit bacterial proliferation and biofilm formation, improve the complex microenvironment surrounding the wound, and promote neovascularization, ultimately accelerating the wound repair.</description><identifier>ISSN: 2688-4062</identifier><identifier>EISSN: 2688-4062</identifier><identifier>DOI: 10.1002/sstr.202400435</identifier><language>eng</language><ispartof>Small structures, 2024-10</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c124t-3b0f2406de3e18fa20c01b272ab734f236f43d9c5f66545c877898690517589d3</cites><orcidid>0000-0003-0714-4966 ; 0000-0002-9613-9247 ; 0000-0002-3118-942X</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,781,785,865,27929,27930</link.rule.ids></links><search><creatorcontrib>Shi, Xiaofeng</creatorcontrib><creatorcontrib>Ma, Qianli</creatorcontrib><creatorcontrib>Jia, Xinlin</creatorcontrib><creatorcontrib>Wu, Zhaofan</creatorcontrib><creatorcontrib>Yu, Chaohong</creatorcontrib><creatorcontrib>Gao, Tian</creatorcontrib><creatorcontrib>Xu, Wei</creatorcontrib><creatorcontrib>Sun, Zhaonan</creatorcontrib><creatorcontrib>Zhang, Jingwei</creatorcontrib><creatorcontrib>Xiong, Huanming</creatorcontrib><creatorcontrib>Mao, Yuanqing</creatorcontrib><title>Multifunctional Carbon Dots Derived from Human Hair for Fast Healing Wounds Together with Oleogels</title><title>Small structures</title><description>In the complex process of wound healing, oleogels (OG) are suitable as the primary component of dressing materials, but they cannot meet the diverse requirements at different healing stages. In this study, a new kind of carbon dots (CrCi‐CDs) prepared by carbonizing human hair, exhibits excellent hemostatic, antibacterial, anti‐inflammatory, and pro‐angiogenic properties and thus supports the various stages of wound healing effectively. Such CrCi‐CDs are incorporated into OG to produce a CrCi‐CD/OG composite material with enhanced multifunctional capabilities, significantly outperforming OG alone. Various experiments in vitro and in vivo confirm that the CrCi‐CDs/OG can rapidly achieve hemostasis at the initial stage of wound formation, subsequently inhibit bacterial proliferation and biofilm formation, improve the complex microenvironment surrounding the wound, and promote neovascularization, ultimately accelerating the wound repair.</description><issn>2688-4062</issn><issn>2688-4062</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><recordid>eNpNkE1LAzEYhIMoWGqvnvMHtr75zh6lta5Q6aXiccnuJm1kdyNJVvHf26KIp5k5zDA8CN0SWBIAepdSjksKlANwJi7QjEqtCw6SXv7z12iR0hucCoIQVaoZap6nPns3jW32YTQ9XpnYhBGvQ054baP_sB12MQy4mgYz4sr4iF2IeGNSxpU1vR8P-DVMY5fwPhxsPtqIP30-4l1vT7lPN-jKmT7Zxa_O0cvmYb-qiu3u8Wl1vy1aQnkuWAPudF92llminaHQAmmooqZRjDvKpOOsK1vhpBRctFopXWpZgiBK6LJjc7T82W1jSClaV79HP5j4VROoz5DqM6T6DxL7Bvt0WoA</recordid><startdate>20241020</startdate><enddate>20241020</enddate><creator>Shi, Xiaofeng</creator><creator>Ma, Qianli</creator><creator>Jia, Xinlin</creator><creator>Wu, Zhaofan</creator><creator>Yu, Chaohong</creator><creator>Gao, Tian</creator><creator>Xu, Wei</creator><creator>Sun, Zhaonan</creator><creator>Zhang, Jingwei</creator><creator>Xiong, Huanming</creator><creator>Mao, Yuanqing</creator><scope>AAYXX</scope><scope>CITATION</scope><orcidid>https://orcid.org/0000-0003-0714-4966</orcidid><orcidid>https://orcid.org/0000-0002-9613-9247</orcidid><orcidid>https://orcid.org/0000-0002-3118-942X</orcidid></search><sort><creationdate>20241020</creationdate><title>Multifunctional Carbon Dots Derived from Human Hair for Fast Healing Wounds Together with Oleogels</title><author>Shi, Xiaofeng ; Ma, Qianli ; Jia, Xinlin ; Wu, Zhaofan ; Yu, Chaohong ; Gao, Tian ; Xu, Wei ; Sun, Zhaonan ; Zhang, Jingwei ; Xiong, Huanming ; Mao, Yuanqing</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c124t-3b0f2406de3e18fa20c01b272ab734f236f43d9c5f66545c877898690517589d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Shi, Xiaofeng</creatorcontrib><creatorcontrib>Ma, Qianli</creatorcontrib><creatorcontrib>Jia, Xinlin</creatorcontrib><creatorcontrib>Wu, Zhaofan</creatorcontrib><creatorcontrib>Yu, Chaohong</creatorcontrib><creatorcontrib>Gao, Tian</creatorcontrib><creatorcontrib>Xu, Wei</creatorcontrib><creatorcontrib>Sun, Zhaonan</creatorcontrib><creatorcontrib>Zhang, Jingwei</creatorcontrib><creatorcontrib>Xiong, Huanming</creatorcontrib><creatorcontrib>Mao, Yuanqing</creatorcontrib><collection>CrossRef</collection><jtitle>Small structures</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Shi, Xiaofeng</au><au>Ma, Qianli</au><au>Jia, Xinlin</au><au>Wu, Zhaofan</au><au>Yu, Chaohong</au><au>Gao, Tian</au><au>Xu, Wei</au><au>Sun, Zhaonan</au><au>Zhang, Jingwei</au><au>Xiong, Huanming</au><au>Mao, Yuanqing</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Multifunctional Carbon Dots Derived from Human Hair for Fast Healing Wounds Together with Oleogels</atitle><jtitle>Small structures</jtitle><date>2024-10-20</date><risdate>2024</risdate><issn>2688-4062</issn><eissn>2688-4062</eissn><abstract>In the complex process of wound healing, oleogels (OG) are suitable as the primary component of dressing materials, but they cannot meet the diverse requirements at different healing stages. In this study, a new kind of carbon dots (CrCi‐CDs) prepared by carbonizing human hair, exhibits excellent hemostatic, antibacterial, anti‐inflammatory, and pro‐angiogenic properties and thus supports the various stages of wound healing effectively. Such CrCi‐CDs are incorporated into OG to produce a CrCi‐CD/OG composite material with enhanced multifunctional capabilities, significantly outperforming OG alone. Various experiments in vitro and in vivo confirm that the CrCi‐CDs/OG can rapidly achieve hemostasis at the initial stage of wound formation, subsequently inhibit bacterial proliferation and biofilm formation, improve the complex microenvironment surrounding the wound, and promote neovascularization, ultimately accelerating the wound repair.</abstract><doi>10.1002/sstr.202400435</doi><orcidid>https://orcid.org/0000-0003-0714-4966</orcidid><orcidid>https://orcid.org/0000-0002-9613-9247</orcidid><orcidid>https://orcid.org/0000-0002-3118-942X</orcidid></addata></record>
fulltext fulltext
identifier ISSN: 2688-4062
ispartof Small structures, 2024-10
issn 2688-4062
2688-4062
language eng
recordid cdi_crossref_primary_10_1002_sstr_202400435
source Wiley Online Library - AutoHoldings Journals; DOAJ Directory of Open Access Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Wiley Online Library (Open Access Collection)
title Multifunctional Carbon Dots Derived from Human Hair for Fast Healing Wounds Together with Oleogels
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-14T00%3A54%3A19IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-crossref&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Multifunctional%20Carbon%20Dots%20Derived%20from%20Human%20Hair%20for%20Fast%20Healing%20Wounds%20Together%20with%20Oleogels&rft.jtitle=Small%20structures&rft.au=Shi,%20Xiaofeng&rft.date=2024-10-20&rft.issn=2688-4062&rft.eissn=2688-4062&rft_id=info:doi/10.1002/sstr.202400435&rft_dat=%3Ccrossref%3E10_1002_sstr_202400435%3C/crossref%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true