PROTAC Degraders of Androgen Receptor‐Integrated Dissolving Microneedles for Androgenetic Alopecia and Recrudescence Treatment via Single Topical Administration

Androgenetic alopecia (AGA) is a transracial and cross‐gender disease worldwide with a youth‐oriented tendency, but it lacks effective treatment. The binding of androgen receptor (AR) and androgen plays an essential role in the occurrence and progression of AGA. Herein, novel proteolysis targeting c...

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Veröffentlicht in:	Small methods 2023-01, Vol.7 (1), p.e2201293-n/a
Hauptverfasser:	Wang, Ruxuan, Zhong, Tengjiang, Bian, Qiong, Zhang, Sai, Ma, Xiaolu, Li, Liming, Xu, Yihua, Gu, Yueting, Yuan, Anran, Hu, Weitong, Qin, Chong, Gao, Jianqing
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Topical Adolescent Alopecia - drug therapy Alopecia - metabolism androgen receptors androgenetic alopecia Androgens - metabolism Androgens - therapeutic use Humans microneedles Minoxidil - therapeutic use proteolysis targeting chimera Proteolysis Targeting Chimera - chemistry Proteolysis Targeting Chimera - therapeutic use Receptors, Androgen - drug effects Receptors, Androgen - metabolism recrudescence
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