Photoimmunotherapy: Artificial Metalloprotein Nanoanalogues: In Situ Catalytic Production of Oxygen to Enhance Photoimmunotherapeutic Inhibition of Primary and Abscopal Tumor Growth (Small 46/2020)

Photoimmunotherapy: Artificial Metalloprotein Nanoanalogues: In Situ Catalytic Production of Oxygen to Enhance Photoimmunotherapeutic Inhibition of Primary and Abscopal Tumor Growth (Small 46/2020)

In article number 2004345, Bang‐Ping Jiang, Xing‐Can Shen, and co‐workers develop one type of brand‐new artificial metalloprotein nanoanalogues for enhanced photoimmunotherapy via reasonably integrating “phototherapy‐enzymatic” RuO2 and model antigen ovalbumin. This ushers a prospect of concurrently...

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Veröffentlicht in:Small (Weinheim an der Bergstrasse, Germany) Germany), 2020-11, Vol.16 (46), p.n/a
Hauptverfasser: Huang, Rongtao, Ding, Zhaoyang, Jiang, Bang‐Ping, Luo, Zilan, Chen, Ting, Guo, Zhengxi, Ji, Shi‐Chen, Liang, Hong, Shen, Xing‐Can
Format: Artikel
Sprache:eng
Schlagworte:
in situ catalysis
metalloprotein nanoanalogues
photoimmunotherapy
ruthenium oxides
tumor hypoxia
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Zusammenfassung:In article number 2004345, Bang‐Ping Jiang, Xing‐Can Shen, and co‐workers develop one type of brand‐new artificial metalloprotein nanoanalogues for enhanced photoimmunotherapy via reasonably integrating “phototherapy‐enzymatic” RuO2 and model antigen ovalbumin. This ushers a prospect of concurrently enhancing photodynamic therapy and reversing the immunosuppressive tumor microenvironment by in situ catalyzing overexpressed H2O2 to produce O2.
ISSN:1613-6810
1613-6829
DOI:10.1002/smll.202070254