Development of Novel Pyridine and Pyrimidine Clubbed Bisindoles as Inhibitors of AKT Pathway

Indoles and their derivatives have long been studied for their anticancer properties. Breast cancer has been treated using indole‐3‐carbinol, Indirubins, and many other naturally occurring indoles as well as their synthesized equivalents. It has been determined that the AKT pathway is a prospective...

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Veröffentlicht in:	ChemistrySelect (Weinheim) 2024-07, Vol.9 (27), p.n/a
Hauptverfasser:	Poonacha, Lisha K., Metri, Prashant K, Xi, Zhang, Ravish, Akshay, Nagaraja, Omantheswara, Kumar, Arun M., Parameshwaraiah, Sindhu M., Swamy Shivananju, Nanjunda, Madegowda, Mahendra, Lobie, Peter E., Babu Shubha, Priya, Pandey, Vijay, Basappa, Basappa
Format:	Artikel
Sprache:	eng
Schlagworte:	AKT pathway AutoDock Bisindoles Molecular dynamics simulation Pyridines Pyrimidines Thiamine hydrochloride
Online-Zugang:	Volltext
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