In–Vitro Anticancer and Antibacterial Activities of Brominated Indeno[1,2‐b]qinoline Amines Supported with Molecular Docking and MCDM

The present study describes mono substituted indeno[1,2‐b]quinolines (3 a–c and 5) have much more antiproliferative potentials than positive controls against A549, HeLa, MCF7 and Hep3B cell lines (IC50 values 1.1–29.6 μg/mL) and show similar cytotoxicity (14.3 % to 19.8 %) to cells such as controls....

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Veröffentlicht in:	ChemistrySelect (Weinheim) 2021-04, Vol.6 (13), p.3286-3295
Hauptverfasser:	Aydın, Ali, Ökten, Salih, Erkan, Sultan, Bulut, Merve, Özcan, Evrencan, Tutar, Ahmet, Eren, Tamer
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibacterial agents Antitumor agents Biological activity Indeno[1,2-b]quinoline amine Molecular docking Multi criteria decision making
Online-Zugang:	Volltext
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