Chemo‐Biocatalytic Oxidative Condensation of Natural Arylpropene with 2‐Aminobenzothiazole into Schiff‐Bases as Potent Anti‐Amyloid Agents: Studies Employing Transgenic C. elegans

Combining natural scaffolds with potent heterocyclic pharmacophores to have extra ordinary potency of synthetic hybrid molecules has gained significant attention as these compounds possess diverse biological activities including ameliorative effects against Alzheimer disease (AD) associated endpoint...

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Veröffentlicht in:	ChemistrySelect (Weinheim) 2018-03, Vol.3 (12), p.3539-3547
Hauptverfasser:	Saima, Kumar, Lalit, Lavekar, Aditya G., Sharma, Tanuj, Shamsuzzama, Equbal, Danish, Siddiqi, Mohammad Imran, Sinha, Arun K., Nazir, Aamir
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer disease Caenorhabditis elegans Chemo-biocatalysis Oxidative condensation Schiffs base
Online-Zugang:	Volltext
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