Synthesis of 2,5‐Disubstituted‐1,3,4‐oxadiazole Derivatives and Their Evaluation as Anticancer and Antimycobacterial Agents

A series of regioisomeric (2,5‐dimethoxybenzoic acid, veratric acid) analogues were prepared by swapping the carboxylic motif to its oxadiazole bioisostere and have been screened for in vitro anticancer studies by using MTT (3‐(4,5‐dimethylthiazol‐2‐yl)‐2,5‐diphenyltetrazolium bromide) colorimetric...

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Veröffentlicht in:	ChemistrySelect (Weinheim) 2017-07, Vol.2 (20), p.5492-5496
Hauptverfasser:	Polkam, Naveen, Kummari, Bhaskar, Rayam, Parsharamulu, Brahma, Umarani, Ganga Modi Naidu, Vegi, Balasubramanian, Sridhar, Anireddy, Jaya Shree
Format:	Artikel
Sprache:	eng
Schlagworte:	1,3,4-Oxadiazole Anticancer activity Bioisosterism Crystallography Veratric acid
Online-Zugang:	Volltext
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