Steroidal Mineralocorticoid Receptor Antagonists: Synthesis and Biology

The development of selective steroidal mineralocorticoid receptor antagonists with improved pharmacological profiles over existing marketed drugs is an attractive goal. Such compounds offer potential for the treatment of hypertension, heart failure and renal disease. With this aim, new spirolactones...

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Veröffentlicht in:	ChemistrySelect (Weinheim) 2017-01, Vol.2 (1), p.175-189
Hauptverfasser:	Yarnold, Christopher, Bainbridge, J. Marie, Boehm, Helen S., Brewer, Mark, Courtney, Stephen, Deboves, Hervé, Di Lucrezia, Raffaella, Giles, Paul, Hamelin, Estelle, Jungmann, Jörn, Leonardi, Amedeo, Meniconi, Mirco, Riva, Carlo, Scheel, Andreas, Selvaratnam, Suganthan, Shanmugathasan, Sakthi, Sironi, Giorgio, Tavecchia, Paolo, Willows, David
Format:	Artikel
Sprache:	eng
Schlagworte:	Antagonist Medicinal Chemistry Mineralocorticoid Receptor Spirolactones Steroids
Online-Zugang:	Volltext
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