Design, Synthesis and Structure‐Activity Relationship Study of Coumarin Benzimidazole Hybrid as Potent Antibacterial and Anticancer Agents

New coumarin‐benzimidazole hybrids (3a–f) have been synthesized from 4‐formylcoumarins and a series of N‐sulphonation (4 a‐f) and N‐methylation (5 a‐f) compounds were obtained from compounds (3a–f). All the synthesized compounds have exhibited good antimicrobial activity. Docking studies provide val...

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Veröffentlicht in:	ChemistrySelect (Weinheim) 2016-09, Vol.1 (15), p.4638-4644
Hauptverfasser:	Holiyachi, Megharaja, Shastri, Samundeeswari L., Chougala, Bahubali M., Shastri, Lokesh A., Joshi, Shrinivas D., Dixit, Sheshagiri R., Nagarajaiah, Honnappa, Sunagar, Vinay A.
Format:	Artikel
Sprache:	eng
Schlagworte:	4-formyl coumarin anticancer antimicrobial coumarin-C4-benzimidazole hybrid molecular docking
Online-Zugang:	Volltext
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