On-line on-chip post-column derivatisation reactions for pre-ionisation of analytes and cluster analysis in gradient µ-liquid chromatography/electrospray mass spectrometry

A system is presented that demonstrates the principle of on‐line and on‐chip post‐column derivatisation reactions in micro‐high‐performance liquid chromatography (µ‐HPLC) hyphenated to electrospray time‐of‐flight mass spectrometry (ESI‐TOFMS). In this µ‐HPLC‐chip‐MS set‐up, the analytes are separate...

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Veröffentlicht in:Rapid communications in mass spectrometry 2002-07, Vol.16 (14), p.1377-1388
Hauptverfasser: Spikmans, Valerie, Lane, Stephen J., Leavens, Bill, Manz, Andreas, Smith, Norman W.
Format: Artikel
Sprache:eng
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