Mass spectral characteristics of okadaic acid and simple derivatives
Electron ionization (EI), chemical ionization (CI) and fast‐atom bombardment (FAB) mass spectra of the marine toxin okadaic acid and its syntheticf methyi, pentafurobenzyl, and trimethylislyl ester and ether derivatives were generated. Several ionization conditions and‐processing methods were used t...
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| Veröffentlicht in: | Rapid communications in mass spectrometry 1991-06, Vol.5 (6), p.283-290 |
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| container_title | Rapid communications in mass spectrometry |
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| creator | Bencsath, F. Aladar Dickey, Robert W. Edmonds, C. G. |
| description | Electron ionization (EI), chemical ionization (CI) and fast‐atom bombardment (FAB) mass spectra of the marine toxin okadaic acid and its syntheticf methyi, pentafurobenzyl, and trimethylislyl ester and ether derivatives were generated. Several ionization conditions and‐processing methods were used to obtain positive‐ and negative‐ion conventional spectra and tandem (MS/MS) spectra. The EF and the positive‐ion CI spectra provided fragment ions characteristic of the structure, and the negative‐ion CI and FAB spectra provided molecular ions. The addition of alkali salts to the FAB matrix resulted in reduced fragmentation and the formation of intense alkali‐metal‐cationized molecules. Pentafluorbenzyle ester derivatives provided intense carboxylate ions under electron‐captute ionization. Analytically useful MS/MS spectra obtained by low‐energy collision‐induced decomposition of the carboxylate anion produced from the tetrasilylated pentafluorobenzylokadaate. |
| doi_str_mv | 10.1002/rcm.1290050608 |
| format | Article |
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Analytically useful MS/MS spectra obtained by low‐energy collision‐induced decomposition of the carboxylate anion produced from the tetrasilylated pentafluorobenzylokadaate.</description><identifier>ISSN: 0951-4198</identifier><identifier>EISSN: 1097-0231</identifier><identifier>DOI: 10.1002/rcm.1290050608</identifier><identifier>PMID: 1804418</identifier><language>eng</language><publisher>London: Heyden & Son Limited</publisher><subject>Analytical, structural and metabolic biochemistry ; Aromatic and heterocyclic compounds ; Biological and medical sciences ; Ethers, Cyclic - analysis ; Fundamental and applied biological sciences. 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Aladar</creatorcontrib><creatorcontrib>Dickey, Robert W.</creatorcontrib><creatorcontrib>Edmonds, C. G.</creatorcontrib><title>Mass spectral characteristics of okadaic acid and simple derivatives</title><title>Rapid communications in mass spectrometry</title><addtitle>Rapid Commun. Mass Spectrom</addtitle><description>Electron ionization (EI), chemical ionization (CI) and fast‐atom bombardment (FAB) mass spectra of the marine toxin okadaic acid and its syntheticf methyi, pentafurobenzyl, and trimethylislyl ester and ether derivatives were generated. Several ionization conditions and‐processing methods were used to obtain positive‐ and negative‐ion conventional spectra and tandem (MS/MS) spectra. The EF and the positive‐ion CI spectra provided fragment ions characteristic of the structure, and the negative‐ion CI and FAB spectra provided molecular ions. The addition of alkali salts to the FAB matrix resulted in reduced fragmentation and the formation of intense alkali‐metal‐cationized molecules. Pentafluorbenzyle ester derivatives provided intense carboxylate ions under electron‐captute ionization. Analytically useful MS/MS spectra obtained by low‐energy collision‐induced decomposition of the carboxylate anion produced from the tetrasilylated pentafluorobenzylokadaate.</description><subject>Analytical, structural and metabolic biochemistry</subject><subject>Aromatic and heterocyclic compounds</subject><subject>Biological and medical sciences</subject><subject>Ethers, Cyclic - analysis</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Heterocyclic compounds, pigments</subject><subject>Marine Toxins - analysis</subject><subject>Mass Spectrometry</subject><subject>Okadaic Acid</subject><subject>Other biological molecules</subject><subject>Spectrometry, Mass, Fast Atom Bombardment</subject><issn>0951-4198</issn><issn>1097-0231</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1991</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkD1PwzAQhi0EKqWwsiFlYUy5S5w6HlGBAEpBQnyM1tWxhWlKKzsU-u8JSkXFxHTDPc99vIwdIwwRIDnzej7ERAJkMIJ8h_URpIghSXGX9UFmGHOU-T47COENADFLoMd6mAPnmPfZxYRCiMLS6MZTHelX8qQb411onA7RwkaLGVXkdETaVRG9V1Fw82VtoqqFVtS4lQmHbM9SHczRpg7Y09Xl4_g6Lu-Lm_F5GWsOeR5LJOSJAGFFChyBppUgNDyTKZeWKMuRBBBqm2TIgSc2N6lMhM0IptBSAzbs5mq_CMEbq5bezcmvFYL6SUO1aahtGq1w0gnLj-ncVFu8e7_tn276FDTV1tO7dmGLSZEicmw52XGfrjbrf7aqh_Hkzw1x57aRmq9fl_xMjUQqMvVyV6iymJTPt4VUMv0GtRaGQA</recordid><startdate>199106</startdate><enddate>199106</enddate><creator>Bencsath, F. 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G.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4088-91a142707f730410abd7a1e459349faa581a70a1cf2514042f8e3927f5a0b0593</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1991</creationdate><topic>Analytical, structural and metabolic biochemistry</topic><topic>Aromatic and heterocyclic compounds</topic><topic>Biological and medical sciences</topic><topic>Ethers, Cyclic - analysis</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Heterocyclic compounds, pigments</topic><topic>Marine Toxins - analysis</topic><topic>Mass Spectrometry</topic><topic>Okadaic Acid</topic><topic>Other biological molecules</topic><topic>Spectrometry, Mass, Fast Atom Bombardment</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Bencsath, F. Aladar</creatorcontrib><creatorcontrib>Dickey, Robert W.</creatorcontrib><creatorcontrib>Edmonds, C. 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Mass Spectrom</addtitle><date>1991-06</date><risdate>1991</risdate><volume>5</volume><issue>6</issue><spage>283</spage><epage>290</epage><pages>283-290</pages><issn>0951-4198</issn><eissn>1097-0231</eissn><abstract>Electron ionization (EI), chemical ionization (CI) and fast‐atom bombardment (FAB) mass spectra of the marine toxin okadaic acid and its syntheticf methyi, pentafurobenzyl, and trimethylislyl ester and ether derivatives were generated. Several ionization conditions and‐processing methods were used to obtain positive‐ and negative‐ion conventional spectra and tandem (MS/MS) spectra. The EF and the positive‐ion CI spectra provided fragment ions characteristic of the structure, and the negative‐ion CI and FAB spectra provided molecular ions. The addition of alkali salts to the FAB matrix resulted in reduced fragmentation and the formation of intense alkali‐metal‐cationized molecules. Pentafluorbenzyle ester derivatives provided intense carboxylate ions under electron‐captute ionization. Analytically useful MS/MS spectra obtained by low‐energy collision‐induced decomposition of the carboxylate anion produced from the tetrasilylated pentafluorobenzylokadaate.</abstract><cop>London</cop><pub>Heyden & Son Limited</pub><pmid>1804418</pmid><doi>10.1002/rcm.1290050608</doi><tpages>8</tpages></addata></record> |
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| ispartof | Rapid communications in mass spectrometry, 1991-06, Vol.5 (6), p.283-290 |
| issn | 0951-4198 1097-0231 |
| language | eng |
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| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | Analytical, structural and metabolic biochemistry Aromatic and heterocyclic compounds Biological and medical sciences Ethers, Cyclic - analysis Fundamental and applied biological sciences. Psychology Heterocyclic compounds, pigments Marine Toxins - analysis Mass Spectrometry Okadaic Acid Other biological molecules Spectrometry, Mass, Fast Atom Bombardment |
| title | Mass spectral characteristics of okadaic acid and simple derivatives |
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