QSAR Models for Prediction of Glycogen Synthase Kinase-3β Inhibitory Activity of Indirubin Derivatives

Glycogen Synthase (GS) Kinase‐3 (GSK‐3), a serine/threonine kinase, isolated and purified as an enzyme capable of phosphorylating and inactivating the enzyme GS is a fascinating enzyme with diverse biological actions in intracellular signaling pathways. A large body of evidence supports speculation...

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Veröffentlicht in:	QSAR & combinatorial science 2008-06, Vol.27 (6), p.718-728
Hauptverfasser:	Lather, Viney, Kristam, Rajendra, Saini, Jagmohan Singh, Karthikeyan, Narasingapuram Arumugam, Balaji, Vitukudi Narayana
Format:	Artikel
Sprache:	eng
Schlagworte:	2D-QSAR 3D-QSAR Glycogen Synthase Kinase (GSK-3) Indirubins PHASE
Online-Zugang:	Volltext
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