Effects of Penta-O-galloyl-β-D-glucose on Human Neutrophil Function: significant Down-Regulation of L-selectin Expression

Penta‐O‐galloyl‐β‐D‐glucose (PGG) occurrs in high concentrations in medicinal herbs such as Rhus chinensis, Paeonia suffruticosa, Acer truncatum and Terminalia chebula, which demonstrate anti‐inflammatory activity. We investigated the effect of PGG on stimulated and non‐stimulated neutrophils in pro...

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Veröffentlicht in:	Phytotherapy research 2013-07, Vol.27 (7), p.986-992
Hauptverfasser:	Kiss, Anna K., Filipek, Agnieszka, Żyżyńska-Granica, Barbara, Naruszewicz, Marek
Format:	Artikel
Sprache:	eng
Schlagworte:	Acer - chemistry Anti-Inflammatory Agents - pharmacology Apoptosis - drug effects CD11b Antigen - metabolism Down-Regulation - drug effects Glucose - pharmacology Humans Hydrolyzable Tannins - pharmacology inflammation Interleukin-8 - biosynthesis L-selectin L-Selectin - metabolism Matrix Metalloproteinase 9 - metabolism neutrophils Neutrophils - drug effects Neutrophils - metabolism Paeonia - chemistry penta-O-galloyl-β-D-glucosel Plant Extracts - pharmacology Reactive Oxygen Species - metabolism Rhus - chemistry Terminalia - chemistry
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