Cryptotanshinone from Salviae Miltiorrhizae Radix Inhibits Sodium-nitroprusside-induced Apoptosis in Neuro-2a Cells

The root of Salvia miltiorrhiza (Salviae miltiorrhizae radix), a herbal medicine has widely been used for the treatment of pain, miscarriage and oedema. In this study, we evaluated the neuroprotective effect of cryptotanshinone (CRT) from Salviae miltiorrhizae radix on sodium‐nitroprusside (SNP)‐ind...

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Veröffentlicht in:	Phytotherapy research 2012-08, Vol.26 (8), p.1211-1219
Hauptverfasser:	Mahesh, Ramalingam, Jung, Hyo Won, Kim, Gun Woo, Kim, Young Shik, Park, Yong-Ki
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antineoplastic Agents, Phytogenic - pharmacology apoptosis Apoptosis - drug effects Biological and medical sciences Caspase 3 - metabolism Cell Line, Tumor Cell Survival cryptotanshinone Cytosol - metabolism Drug Evaluation, Preclinical General pharmacology Glutamate-Cysteine Ligase - genetics Glutamate-Cysteine Ligase - metabolism Lipid Peroxidation MAP Kinase Signaling System Medical sciences Membrane Potential, Mitochondrial - drug effects Mice mitochondria Mitochondria - drug effects Mitochondria - metabolism Neuroblastoma - genetics Neuroblastoma - metabolism Neuroblastoma - pathology Neuroprotective Agents - pharmacology NF-kappa B - antagonists & inhibitors NF-kappa B - metabolism Nitroprusside - adverse effects Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Phenanthrenes - pharmacology Reactive Nitrogen Species - metabolism Reactive Oxygen Species - metabolism RNA, Messenger - genetics Salvia miltiorrhiza Salvia miltiorrhiza - chemistry Salviae miltiorrhizae radix sodium nitroprusside
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