Protective Effect of Lycium barbarum Polysaccharides Against Doxorubicin‐induced Testicular Toxicity in Rats

The present study aimed to investigate whether Lycium barbarum polysaccharides (LBP) would protect against doxorubicin (DOX)‐induced testicular toxicity. Male Sprague‐Dawley rats were treated with distilled water (4 mL/kg) or LBP (200 mg/kg, p.o.) daily for 10 days and followed by saline (0.9 %, 10 ...

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Veröffentlicht in:	Phytotherapy research 2012-05, Vol.26 (5), p.716-721
Hauptverfasser:	Xin, Yan‐Fei, You, Zhen‐Qiang, Gao, Hai‐yan, Zhou, Guo‐Liang, Chen, Yun‐Xiang, Yu, Jian, Xuan, Yao‐Xian
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibiotics, Antineoplastic - toxicity antioxidant Antioxidants - pharmacology Biological and medical sciences doxorubicin Doxorubicin - toxicity Drugs, Chinese Herbal - pharmacology General pharmacology Humans intravenous injection Lipid Peroxidation - drug effects Lycium - chemistry Lycium barbarum Lycium barbarum polysaccharides Male Malondialdehyde - metabolism Medical sciences Organ Size - drug effects Organ Specificity oxidative stress Oxidative Stress - drug effects Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments polysaccharides protective effect Random Allocation Rats Rats, Sprague-Dawley seminiferous tubules Seminiferous Tubules - drug effects sperm concentration spermatozoa Spermatozoa - drug effects Spermatozoa - physiology testicular toxicity Testis - drug effects Testis - metabolism Testis - pathology testosterone Testosterone - blood toxicity
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