Sclerocarya birrea (a. rich) hochst. ['marula'] (anacardiaceae): a review of its phytochemistry, pharmacology and toxicology and its ethnomedicinal uses
A plethora of ethnotherapeutic properties and pharmacological actions have been attributed to Sclerocarya birrea (family: Anacardiaceae). It is one of the most highly valued indigenous trees of southern Africa. Reports in biomedical literature have indicated the presence of medicinally-important che...
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| Veröffentlicht in: | Phytotherapy research 2010-05, Vol.24 (5), p.633-639 |
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| creator | Ojewole, John A.O Mawoza, Tariro Chiwororo, Witness D.H Owira, Peter M.O |
| description | A plethora of ethnotherapeutic properties and pharmacological actions have been attributed to Sclerocarya birrea (family: Anacardiaceae). It is one of the most highly valued indigenous trees of southern Africa. Reports in biomedical literature have indicated the presence of medicinally-important chemical constituents in the plant, notably: polyphenols, tannins, coumarins, flavonoids, triterpenoids, phytosterols, and so forth. Pharmacological studies by various groups of investigators have shown that S. birrea possesses antidiarrhoeal, antidiabetic, anti-inflammatory, antimicrobial, antiplasmodial, antihypertensive, anticonvulsant, antinociceptive and antioxidant properties, thus lending pharmacological support to the plant's folkloric, ethnotherapeutic uses in South African traditional medicine. In view of the immense medicinal importance of the plant, this review aimed at compiling all currently available information on S. birrea's chemical constituents, as well as its ethnomedicinal, pharmacological and toxicological properties. Copyright © 2009 John Wiley & Sons, Ltd. |
| doi_str_mv | 10.1002/ptr.3080 |
| format | Article |
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Pharmacological studies by various groups of investigators have shown that S. birrea possesses antidiarrhoeal, antidiabetic, anti-inflammatory, antimicrobial, antiplasmodial, antihypertensive, anticonvulsant, antinociceptive and antioxidant properties, thus lending pharmacological support to the plant's folkloric, ethnotherapeutic uses in South African traditional medicine. In view of the immense medicinal importance of the plant, this review aimed at compiling all currently available information on S. birrea's chemical constituents, as well as its ethnomedicinal, pharmacological and toxicological properties. 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Drug treatments ; Phytotherapy ; Plant Bark - chemistry ; Plant Extracts - chemistry ; Plant Extracts - pharmacology ; Plant Leaves - chemistry ; Sclerocarya birrea ('Marula') ; toxicological actions</subject><ispartof>Phytotherapy research, 2010-05, Vol.24 (5), p.633-639</ispartof><rights>Copyright © 2009 John Wiley & Sons, Ltd.</rights><rights>2015 INIST-CNRS</rights><rights>Copyright (c) 2009 John Wiley & Sons, Ltd.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4120-3e663863103c49b7f2f1df316c09328902a1a72e5850c916bdb61ec66b2a5cdf3</citedby><cites>FETCH-LOGICAL-c4120-3e663863103c49b7f2f1df316c09328902a1a72e5850c916bdb61ec66b2a5cdf3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fptr.3080$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fptr.3080$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,777,781,1412,27905,27906,45555,45556</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=22680976$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/20013815$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ojewole, John A.O</creatorcontrib><creatorcontrib>Mawoza, Tariro</creatorcontrib><creatorcontrib>Chiwororo, Witness D.H</creatorcontrib><creatorcontrib>Owira, Peter M.O</creatorcontrib><title>Sclerocarya birrea (a. rich) hochst. ['marula'] (anacardiaceae): a review of its phytochemistry, pharmacology and toxicology and its ethnomedicinal uses</title><title>Phytotherapy research</title><addtitle>Phytother. Res</addtitle><description>A plethora of ethnotherapeutic properties and pharmacological actions have been attributed to Sclerocarya birrea (family: Anacardiaceae). It is one of the most highly valued indigenous trees of southern Africa. Reports in biomedical literature have indicated the presence of medicinally-important chemical constituents in the plant, notably: polyphenols, tannins, coumarins, flavonoids, triterpenoids, phytosterols, and so forth. Pharmacological studies by various groups of investigators have shown that S. birrea possesses antidiarrhoeal, antidiabetic, anti-inflammatory, antimicrobial, antiplasmodial, antihypertensive, anticonvulsant, antinociceptive and antioxidant properties, thus lending pharmacological support to the plant's folkloric, ethnotherapeutic uses in South African traditional medicine. In view of the immense medicinal importance of the plant, this review aimed at compiling all currently available information on S. birrea's chemical constituents, as well as its ethnomedicinal, pharmacological and toxicological properties. Copyright © 2009 John Wiley & Sons, Ltd.</description><subject>Africa, Southern</subject><subject>Anacardiaceae - chemistry</subject><subject>Anacardiaceae - toxicity</subject><subject>Animals</subject><subject>Biological and medical sciences</subject><subject>chemical constituents</subject><subject>complementary medicine</subject><subject>Fruit - chemistry</subject><subject>General pharmacology</subject><subject>Humans</subject><subject>Medical sciences</subject><subject>Medicine, African Traditional</subject><subject>Pharmacognosy. Homeopathy. Health food</subject><subject>pharmacological properties</subject><subject>Pharmacology. Drug treatments</subject><subject>Phytotherapy</subject><subject>Plant Bark - chemistry</subject><subject>Plant Extracts - chemistry</subject><subject>Plant Extracts - pharmacology</subject><subject>Plant Leaves - chemistry</subject><subject>Sclerocarya birrea ('Marula')</subject><subject>toxicological actions</subject><issn>0951-418X</issn><issn>1099-1573</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp10M1u1DAQB3ALgehSkHgC8AW1lcgythMn5oYWKKjlQ7QVSAhZE8dpDNl4ZWdp8yY8Ll7tUrhwskb-zXj8J-QhgzkD4M9WY5gLqOAWmTFQKmNFKW6TGaiCZTmrvuyRezF-BwDFIb9L9jgAExUrZuTXmelt8AbDhLR2IVikhzinwZnuiHbedHGc068HSwzrHg--pcsBk24cGov26DlFGuxPZ6-ob6kbI11105ja7NLFMUxPU41hicb3_nKiODR09Nfun3LTY8du8EvbOOMG7Ok62nif3Gmxj_bB7twnF69fnS_eZKcfjt8uXpxmJmccMmGlFJUUDITJVV22vGVNK5g0oASvFHBkWHJbVAUYxWTd1JJZI2XNsTBJ7pPD7VwTfIzBtnoVXPrtpBnoTbg6has34Sb6aEtX6zotewP_pJnAkx3AaLBvAw7Gxb-OywpUKZPLtu7K9Xb674P64_mn3cM7nyK11zceww8tS1EW-vP7Y30iX77ji8WJ3sx_vPUteo2XIe1wccbTksAqoXJRiN-vzqm0</recordid><startdate>201005</startdate><enddate>201005</enddate><creator>Ojewole, John A.O</creator><creator>Mawoza, Tariro</creator><creator>Chiwororo, Witness D.H</creator><creator>Owira, Peter M.O</creator><general>John Wiley & Sons, Ltd</general><general>Wiley</general><scope>FBQ</scope><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>201005</creationdate><title>Sclerocarya birrea (a. rich) hochst. ['marula'] (anacardiaceae): a review of its phytochemistry, pharmacology and toxicology and its ethnomedicinal uses</title><author>Ojewole, John A.O ; Mawoza, Tariro ; Chiwororo, Witness D.H ; Owira, Peter M.O</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4120-3e663863103c49b7f2f1df316c09328902a1a72e5850c916bdb61ec66b2a5cdf3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>Africa, Southern</topic><topic>Anacardiaceae - chemistry</topic><topic>Anacardiaceae - toxicity</topic><topic>Animals</topic><topic>Biological and medical sciences</topic><topic>chemical constituents</topic><topic>complementary medicine</topic><topic>Fruit - chemistry</topic><topic>General pharmacology</topic><topic>Humans</topic><topic>Medical sciences</topic><topic>Medicine, African Traditional</topic><topic>Pharmacognosy. Homeopathy. Health food</topic><topic>pharmacological properties</topic><topic>Pharmacology. Drug treatments</topic><topic>Phytotherapy</topic><topic>Plant Bark - chemistry</topic><topic>Plant Extracts - chemistry</topic><topic>Plant Extracts - pharmacology</topic><topic>Plant Leaves - chemistry</topic><topic>Sclerocarya birrea ('Marula')</topic><topic>toxicological actions</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ojewole, John A.O</creatorcontrib><creatorcontrib>Mawoza, Tariro</creatorcontrib><creatorcontrib>Chiwororo, Witness D.H</creatorcontrib><creatorcontrib>Owira, Peter M.O</creatorcontrib><collection>AGRIS</collection><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><jtitle>Phytotherapy research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ojewole, John A.O</au><au>Mawoza, Tariro</au><au>Chiwororo, Witness D.H</au><au>Owira, Peter M.O</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Sclerocarya birrea (a. rich) hochst. 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Pharmacological studies by various groups of investigators have shown that S. birrea possesses antidiarrhoeal, antidiabetic, anti-inflammatory, antimicrobial, antiplasmodial, antihypertensive, anticonvulsant, antinociceptive and antioxidant properties, thus lending pharmacological support to the plant's folkloric, ethnotherapeutic uses in South African traditional medicine. In view of the immense medicinal importance of the plant, this review aimed at compiling all currently available information on S. birrea's chemical constituents, as well as its ethnomedicinal, pharmacological and toxicological properties. Copyright © 2009 John Wiley & Sons, Ltd.</abstract><cop>Chichester, UK</cop><pub>John Wiley & Sons, Ltd</pub><pmid>20013815</pmid><doi>10.1002/ptr.3080</doi><tpages>7</tpages></addata></record> |
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| subjects | Africa, Southern Anacardiaceae - chemistry Anacardiaceae - toxicity Animals Biological and medical sciences chemical constituents complementary medicine Fruit - chemistry General pharmacology Humans Medical sciences Medicine, African Traditional Pharmacognosy. Homeopathy. Health food pharmacological properties Pharmacology. Drug treatments Phytotherapy Plant Bark - chemistry Plant Extracts - chemistry Plant Extracts - pharmacology Plant Leaves - chemistry Sclerocarya birrea ('Marula') toxicological actions |
| title | Sclerocarya birrea (a. rich) hochst. ['marula'] (anacardiaceae): a review of its phytochemistry, pharmacology and toxicology and its ethnomedicinal uses |
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