ESP-102, a combined extract of Angelica gigas, Saururus chinensis and Schizandra chinensis, protects against glutamate-induced toxicity in primary cultures of rat cortical cells

It was reported previously that ESP-102, a combined extract of Angelica gigas, Saururus chinensis and Schizandra chinensis, significantly improved scopolamine-induced memory impairment in mice and protected primary cultured rat cortical cells against glutamate-induced toxicity. To corroborate this e...

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Veröffentlicht in:	Phytotherapy research 2009-11, Vol.23 (11), p.1587-1591
Hauptverfasser:	Ma, Choong Je, Kim, Seung Hyun, Lee, Ki Yong, Oh, Taehwan, Kim, Sun Yeou, Sung, Sang Hyun, Kim, Young Choong
Format:	Artikel
Sprache:	eng
Schlagworte:	Angelica - chemistry Animals antioxidative activity Biological and medical sciences Calcium - metabolism Cell Survival Cells, Cultured Cerebral Cortex - cytology ESP-102 General pharmacology glutamate Glutamic Acid - toxicity Glutathione Peroxidase - metabolism Glutathione Reductase - metabolism Medical sciences Membrane Potential, Mitochondrial - drug effects Neurons - drug effects Neurons - enzymology neuroprotective activity Nitric Oxide - biosynthesis Oxidative Stress - drug effects Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Plant Extracts - pharmacology Rats Rats, Sprague-Dawley Reactive Oxygen Species - metabolism Saururaceae - chemistry Schisandra - chemistry Superoxide Dismutase - metabolism
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