Inhibition of human P450 enzymes by natural extracts used in traditional medicine

Different medicinal plants are widely used in Cuba and Mexico to treat several disorders. This paper reports in vitro inhibitory effects on the P450 system of herbal products commonly used by people in Cuba and Mexico in traditional medicine for decades. Experiments were conducted in human liver mic...

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Veröffentlicht in:	Phytotherapy research 2009-02, Vol.23 (2), p.279-282
Hauptverfasser:	Rodeiro, Idania, Donato, María T, Jimenez, Nuria, Garrido, Gabino, Molina-Torres, Jorge, Menendez, Roberto, Castell, José V, Gómez-Lechón, María J
Format:	Artikel
Sprache:	eng
Schlagworte:	Asteraceae - chemistry Biological and medical sciences CYP1A1/2 CYP2D6 CYP3A4 Cytochrome P-450 Enzyme Inhibitors Female Flavonoids - pharmacology General pharmacology Herb-Drug Interactions human liver microsomes Humans Hydrocharitaceae - chemistry Male Mangifera - chemistry Medical sciences medicinal plants Medicine, Traditional Microsomes, Liver - drug effects Microsomes, Liver - enzymology Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Phenols - pharmacology Phytotherapy Plant Extracts - pharmacology Plants, Medicinal - metabolism Polyphenols Polyunsaturated Alkamides - pharmacology
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