Antiparkinson drug - Mucuna pruriens shows antioxidant and metal chelating activity

Parkinson's disease is a neurodegenerative disorder for which no neurorestorative therapeutic treatment is currently available. Oxidative stress plays an important role in the pathophysiology of Parkinson's disease. The ancient Indian medical system, Ayurveda, traditionally uses Mucuna pru...

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Veröffentlicht in:	Phytotherapy research 2008-01, Vol.22 (1), p.6-11
Hauptverfasser:	Dhanasekaran, Muralikrishnan, Tharakan, Binu, Manyam, Bala V
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antioxidants - chemistry Antioxidants - pharmacology Antiparkinson Agents - chemistry Antiparkinson Agents - pharmacology Biological and medical sciences Brain - drug effects Brain - metabolism Chelating Agents - chemistry Chelating Agents - pharmacology Cotyledon - chemistry deoxyribose sugar damage DNA Damage - drug effects Flavonoids - metabolism Free Radical Scavengers - chemistry Free Radical Scavengers - pharmacology General pharmacology Glutathione - metabolism iron chelation lipid peroxidation Lipid Peroxidation - drug effects Male Medical sciences Mucuna - chemistry Mucuna pruriens Oxidative Stress - drug effects Parkinson's disease Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Phenols - metabolism Plant Extracts - chemistry Plant Extracts - pharmacology Polyphenols Rats Rats, Sprague-Dawley Reactive Oxygen Species - metabolism
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