Flavanoid of Drynaria fortunei protects against gentamicin ototoxicity

A ﬂavanoid fraction (FF) from Drynaria fortunei, was investigated to see if it has the protective and ameliorative effects against gentamicin (GM) ototoxicity in guinea pigs (n = 36). Eleven (GM‐group) animals received GM 100 mg/kg/day. Eleven (GMFF‐group) animals received the same dose of GM but 2...

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Veröffentlicht in:	Phytotherapy research 2004-08, Vol.18 (8), p.609-614
Hauptverfasser:	Long, M, Smouha, E.E, Qiu, D, Li, F, Johnson, F, Luft, B
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Bacterial Agents - administration & dosage Anti-Bacterial Agents - pharmacology Anti-Bacterial Agents - therapeutic use Biological and medical sciences Drynaria fortunei Escherichia coli - drug effects Evoked Potentials, Auditory, Brain Stem - drug effects Flavones - administration & dosage Flavones - pharmacology Flavones - therapeutic use General pharmacology gentamicin Gentamicins Gu Sui Bu Guinea Pigs hair cell repairing Hair Cells, Auditory, Inner - drug effects Hair Cells, Auditory, Inner - ultrastructure Hair Cells, Auditory, Outer - drug effects Hair Cells, Auditory, Outer - ultrastructure Hearing Loss - chemically induced Hearing Loss - prevention & control Medical sciences Microbial Sensitivity Tests Mycobacterium avium - drug effects ototoxicity Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Phytotherapy Plant Extracts - administration & dosage Plant Extracts - pharmacology Plant Extracts - therapeutic use Polypodiaceae ﬂavanoid
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