Cytotoxicity and antibacterial activity of Sida rhombifolia (Malvaceae) grown in Bangladesh

The cytotoxicity and antibacterial activities of crude extracts from the leaves of Sida rhombifolia were investigated. The ethyl acetate extract showed potent cytotoxicity with LC50 values (5.41 ppm) comparable to the reference standard, gallic acid. All the extracts showed weak antibacterial activi...

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Veröffentlicht in:	Phytotherapy research 2003-09, Vol.17 (8), p.973-975
Hauptverfasser:	Ekramul Islam, M., Ekramul Haque, M., Mosaddik, M. A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Infective Agents - administration & dosage Anti-Infective Agents - pharmacology Anti-Infective Agents - therapeutic use antibacterial Artemia - drug effects Bangladesh cytotoxicity Gallic Acid - pharmacology Gram-Negative Bacteria - drug effects Gram-Positive Bacteria - drug effects Humans Malvaceae Microbial Sensitivity Tests Phytotherapy Plant Extracts - administration & dosage Plant Extracts - pharmacology Plant Extracts - therapeutic use Plant Leaves Sida rhombifolia
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Zusammenfassung:	The cytotoxicity and antibacterial activities of crude extracts from the leaves of Sida rhombifolia were investigated. The ethyl acetate extract showed potent cytotoxicity with LC50 values (5.41 ppm) comparable to the reference standard, gallic acid. All the extracts showed weak antibacterial activity against both Gram‐positive and Gram‐negative test organisms. Copyright © 2003 John Wiley & Sons, Ltd.
ISSN:	0951-418X 1099-1573
DOI:	10.1002/ptr.1294