Effect of pentosan, a novel cancer chemotherapeutic agent, on prostate cancer cell growth and motility

Pentosan is a new chemotherapeutic drug which is currently in Phase I clinical trials. In our experimental systems, in vivo, pentosan inhibits the growth of the highly metastatic MAT‐LyLu (MLL) Dunning R3327 prostate cancer cell line only at toxic doses and has no apparent effect on growth in vitro....

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Veröffentlicht in:	The Prostate 1992, Vol.20 (3), p.233-241
Hauptverfasser:	Pienta, Kenneth J., Murphy, Brian C., Isaacs, William B., Isaacs, John T., Coffey, Donald S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antineoplastic agents Antineoplastic Agents - pharmacology Biological and medical sciences Cell Division - drug effects Cell Movement - drug effects chemotherapeutic drug Chemotherapy Male Medical sciences MLL Pentosan Sulfuric Polyester - pharmacology Pharmacology. Drug treatments Phase I clinical trials Prostatic Neoplasms - pathology Rats Tumor Cells, Cultured
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