Free testosterone in carcinoma of the prostate
Serum concentrations of testosterone (total T), sex hormone‐binding globulin (SHBG), and albumin (A) have been measured, and from these values the free testosterone (free T) has been calculated in the following groups: 50 patients recalled 1‐2 years after prostatectomy for benign prostatic hyperplas...
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| Veröffentlicht in: | The Prostate 1985, Vol.7 (4), p.363-367 |
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| container_issue | 4 |
| container_start_page | 363 |
| container_title | The Prostate |
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| creator | Levell, M. J. Rowe, E. Glashan, R. W. Pidcock, N. B. Siddall, J. K. |
| description | Serum concentrations of testosterone (total T), sex hormone‐binding globulin (SHBG), and albumin (A) have been measured, and from these values the free testosterone (free T) has been calculated in the following groups: 50 patients recalled 1‐2 years after prostatectomy for benign prostatic hyperplasia (BPH); 21 patients with BPH at first presentation; and 80 patients with carcinoma of the prostate (CaP) divided into 47 without clinical or radiological evidence of metastases (Mo) and 33 with metastases (M+). The Mo patients were further subdivided by the size of the prostate. Free T showed no change with age in either of the CaP groups. In both of the BPH groups free T fell with age so that in the patients aged 65 or less it was above the mean CaP level and in patients aged 75 or more it was similar to the CaP level. SHBG rose with age so that total testosterone values were a poor guide to free T. Neither presence of metastases nor prostate size in Mo patients was related to marked differences of free T. |
| doi_str_mv | 10.1002/pros.2990070404 |
| format | Article |
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J. ; Rowe, E. ; Glashan, R. W. ; Pidcock, N. B. ; Siddall, J. K.</creator><creatorcontrib>Levell, M. J. ; Rowe, E. ; Glashan, R. W. ; Pidcock, N. B. ; Siddall, J. K.</creatorcontrib><description>Serum concentrations of testosterone (total T), sex hormone‐binding globulin (SHBG), and albumin (A) have been measured, and from these values the free testosterone (free T) has been calculated in the following groups: 50 patients recalled 1‐2 years after prostatectomy for benign prostatic hyperplasia (BPH); 21 patients with BPH at first presentation; and 80 patients with carcinoma of the prostate (CaP) divided into 47 without clinical or radiological evidence of metastases (Mo) and 33 with metastases (M+). The Mo patients were further subdivided by the size of the prostate. Free T showed no change with age in either of the CaP groups. In both of the BPH groups free T fell with age so that in the patients aged 65 or less it was above the mean CaP level and in patients aged 75 or more it was similar to the CaP level. SHBG rose with age so that total testosterone values were a poor guide to free T. Neither presence of metastases nor prostate size in Mo patients was related to marked differences of free T.</description><identifier>ISSN: 0270-4137</identifier><identifier>EISSN: 1097-0045</identifier><identifier>DOI: 10.1002/pros.2990070404</identifier><identifier>CODEN: PRSTDS</identifier><language>eng</language><publisher>New York: Wiley Subscription Services, Inc., A Wiley Company</publisher><subject>benign prostatic hyperplasia ; Biological and medical sciences ; free testosterone ; Medical sciences ; Nephrology. Urinary tract diseases ; prostatic cancer ; sex hormone-binding globulin ; Tumors of the urinary system ; Urinary tract. Prostate gland</subject><ispartof>The Prostate, 1985, Vol.7 (4), p.363-367</ispartof><rights>Copyright © 1985 Wiley‐Liss, Inc., A Wiley Company</rights><rights>1986 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3584-a7362edc9f4945540848619191b443bb8a4a68fe59846c3211e7d914cc2b689a3</citedby><cites>FETCH-LOGICAL-c3584-a7362edc9f4945540848619191b443bb8a4a68fe59846c3211e7d914cc2b689a3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fpros.2990070404$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fpros.2990070404$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1417,4024,27923,27924,27925,45574,45575</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=8638005$$DView record in Pascal Francis$$Hfree_for_read</backlink></links><search><creatorcontrib>Levell, M. J.</creatorcontrib><creatorcontrib>Rowe, E.</creatorcontrib><creatorcontrib>Glashan, R. W.</creatorcontrib><creatorcontrib>Pidcock, N. B.</creatorcontrib><creatorcontrib>Siddall, J. K.</creatorcontrib><title>Free testosterone in carcinoma of the prostate</title><title>The Prostate</title><addtitle>Prostate</addtitle><description>Serum concentrations of testosterone (total T), sex hormone‐binding globulin (SHBG), and albumin (A) have been measured, and from these values the free testosterone (free T) has been calculated in the following groups: 50 patients recalled 1‐2 years after prostatectomy for benign prostatic hyperplasia (BPH); 21 patients with BPH at first presentation; and 80 patients with carcinoma of the prostate (CaP) divided into 47 without clinical or radiological evidence of metastases (Mo) and 33 with metastases (M+). The Mo patients were further subdivided by the size of the prostate. Free T showed no change with age in either of the CaP groups. In both of the BPH groups free T fell with age so that in the patients aged 65 or less it was above the mean CaP level and in patients aged 75 or more it was similar to the CaP level. SHBG rose with age so that total testosterone values were a poor guide to free T. Neither presence of metastases nor prostate size in Mo patients was related to marked differences of free T.</description><subject>benign prostatic hyperplasia</subject><subject>Biological and medical sciences</subject><subject>free testosterone</subject><subject>Medical sciences</subject><subject>Nephrology. Urinary tract diseases</subject><subject>prostatic cancer</subject><subject>sex hormone-binding globulin</subject><subject>Tumors of the urinary system</subject><subject>Urinary tract. Prostate gland</subject><issn>0270-4137</issn><issn>1097-0045</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1985</creationdate><recordtype>article</recordtype><recordid>eNqFkL1PwzAQxS0EEqUws2ZgTXu2L_4QE6poAVVtxYc6Wo7riECbVHYk2v-eVEFFTOiGW97vvXtHyDWFAQVgw22o44BpDSABAU9Ij4KWKQBmp6QHTEKKlMtzchHjB0DLAOuRwTh4nzQ-NnVsfKgrn5RV4mxwZVVvbFIXSfPuk4N5Yxt_Sc4Ku47-6mf3ydv4_nX0kE7nk8fR3TR1PFOYWskF8yunC9SYZQgKlaC6nRyR57myaIUqfKYVCscZpV6uNEXnWC6UtrxPhp2va4Nj8IXZhnJjw95QMIe65nCR-a3bEjcdsbXR2XURbOXKeMSU4Aoga2W3neyrXPv9f65m8Tx_-ROSdnTZPmt3pG34NEJymZnlbGLGS_0kF1KYGf8GVtR0nw</recordid><startdate>1985</startdate><enddate>1985</enddate><creator>Levell, M. J.</creator><creator>Rowe, E.</creator><creator>Glashan, R. W.</creator><creator>Pidcock, N. B.</creator><creator>Siddall, J. K.</creator><general>Wiley Subscription Services, Inc., A Wiley Company</general><general>Wiley-Liss</general><scope>BSCLL</scope><scope>IQODW</scope><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>1985</creationdate><title>Free testosterone in carcinoma of the prostate</title><author>Levell, M. J. ; Rowe, E. ; Glashan, R. W. ; Pidcock, N. B. ; Siddall, J. K.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3584-a7362edc9f4945540848619191b443bb8a4a68fe59846c3211e7d914cc2b689a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1985</creationdate><topic>benign prostatic hyperplasia</topic><topic>Biological and medical sciences</topic><topic>free testosterone</topic><topic>Medical sciences</topic><topic>Nephrology. Urinary tract diseases</topic><topic>prostatic cancer</topic><topic>sex hormone-binding globulin</topic><topic>Tumors of the urinary system</topic><topic>Urinary tract. Prostate gland</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Levell, M. J.</creatorcontrib><creatorcontrib>Rowe, E.</creatorcontrib><creatorcontrib>Glashan, R. W.</creatorcontrib><creatorcontrib>Pidcock, N. B.</creatorcontrib><creatorcontrib>Siddall, J. K.</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>CrossRef</collection><jtitle>The Prostate</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Levell, M. J.</au><au>Rowe, E.</au><au>Glashan, R. W.</au><au>Pidcock, N. B.</au><au>Siddall, J. K.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Free testosterone in carcinoma of the prostate</atitle><jtitle>The Prostate</jtitle><addtitle>Prostate</addtitle><date>1985</date><risdate>1985</risdate><volume>7</volume><issue>4</issue><spage>363</spage><epage>367</epage><pages>363-367</pages><issn>0270-4137</issn><eissn>1097-0045</eissn><coden>PRSTDS</coden><abstract>Serum concentrations of testosterone (total T), sex hormone‐binding globulin (SHBG), and albumin (A) have been measured, and from these values the free testosterone (free T) has been calculated in the following groups: 50 patients recalled 1‐2 years after prostatectomy for benign prostatic hyperplasia (BPH); 21 patients with BPH at first presentation; and 80 patients with carcinoma of the prostate (CaP) divided into 47 without clinical or radiological evidence of metastases (Mo) and 33 with metastases (M+). The Mo patients were further subdivided by the size of the prostate. Free T showed no change with age in either of the CaP groups. In both of the BPH groups free T fell with age so that in the patients aged 65 or less it was above the mean CaP level and in patients aged 75 or more it was similar to the CaP level. SHBG rose with age so that total testosterone values were a poor guide to free T. Neither presence of metastases nor prostate size in Mo patients was related to marked differences of free T.</abstract><cop>New York</cop><pub>Wiley Subscription Services, Inc., A Wiley Company</pub><doi>10.1002/pros.2990070404</doi><tpages>5</tpages></addata></record> |
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| identifier | ISSN: 0270-4137 |
| ispartof | The Prostate, 1985, Vol.7 (4), p.363-367 |
| issn | 0270-4137 1097-0045 |
| language | eng |
| recordid | cdi_crossref_primary_10_1002_pros_2990070404 |
| source | Wiley Online Library Journals Frontfile Complete |
| subjects | benign prostatic hyperplasia Biological and medical sciences free testosterone Medical sciences Nephrology. Urinary tract diseases prostatic cancer sex hormone-binding globulin Tumors of the urinary system Urinary tract. Prostate gland |
| title | Free testosterone in carcinoma of the prostate |
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