The oncogenic potential of a prostate cancer-derived androgen receptor mutant

BACKGROUND The role of androgen receptor (AR) mutations in the initiation of prostate cancer (CaP) remains unclear. The purpose of this study was to assess the influence of an AR mutation on prostate tumorigenesis and to determine the resulting molecular alterations. METHODS Wild‐type AR (ARWT) or t...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The Prostate 2007-05, Vol.67 (6), p.591-602
Hauptverfasser:	Shi, Xu-Bao, Xue, Lingru, Tepper, Clifford G., Gandour-Edwards, Regina, Ghosh, Paramita, Kung, Hsing-Jien, deVere White, Ralph W.
Format:	Artikel
Sprache:	eng
Schlagworte:	androgen receptor mutation Animals Biological and medical sciences Biomarkers, Tumor - genetics Biomarkers, Tumor - metabolism Carcinogenicity Tests Cell Line, Transformed Cell Proliferation Epithelial Cells - metabolism Epithelial Cells - pathology Gene Expression Profiling Gene Expression Regulation, Neoplastic Gynecology. Andrology. Obstetrics Humans Male Male genital diseases Medical sciences Mice Mice, Nude Mutation Neoplasm Transplantation Nephrology. Urinary tract diseases Oligonucleotide Array Sequence Analysis Prostate - cytology prostate cancer Prostatic Neoplasms - genetics Prostatic Neoplasms - metabolism Prostatic Neoplasms - pathology Receptors, Androgen - genetics Receptors, Androgen - metabolism Transfection tumorigenesis Tumors Tumors of the urinary system Urinary tract. Prostate gland
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!