Effects of sequential treatments with chemotherapeutic drugs followed by TRAIL on prostate cancer in vitro and in vivo

BACKGROUND Tumor necrosis factor related apoptosis‐inducing ligand/Apo2 ligand (TRAIL/Apo‐2L) is a novel anticancer agent, capable of inducing apoptosis preferentially in tumor and transformed cells. TRAIL‐R1/death receptor (DR)4 and TRAIL‐R2/DR5 are members of the tumor necrosis factor (TNF) recept...

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Veröffentlicht in:The Prostate 2005-02, Vol.62 (2), p.165-186
Hauptverfasser: Shankar, Sharmila, Chen, Xufen, Srivastava, Rakesh K.
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Sprache:eng
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