Survey of the DNA binding properties of natural and synthetic polyamino compounds

Using a flourescence‐detected ethidium displacement assay, the calf thymus DNA complexation properties of 27 mono‐, di‐, tri‐, tetra‐ and hexacationic polyamines were determined. The DNA‐binding affinity of these polyamine compounds increased with increasing cationic charge on the polyamine. Althoug...

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Veröffentlicht in:	Journal of physical organic chemistry 1992-08, Vol.5 (8), p.461-466
Hauptverfasser:	Stewart, Kent D., Gray, Thomas A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Fundamental and applied biological sciences. Psychology Interactions. Associations Intermolecular phenomena Molecular biophysics
Online-Zugang:	Volltext
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