Synthesis and rational design of anti-inflammatory compounds: N-phenyl-cyclohexenyl sulfonamide derivatives

The synthesis of (±)‐ethyl 6‐[N‐(2‐chloro‐4‐fluorophenyl)sulfamoyl]cyclohex‐1‐ene‐1‐carboxylate (5n) has been reproduced from a method previously described and served as the background for the preparation of a nitro derivative, potentially useful as an anti‐inflammatory agent. Furthermore, a structu...

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Veröffentlicht in:	Journal of physical organic chemistry 2009-12, Vol.22 (12), p.1188-1192
Hauptverfasser:	Lloret, Gustavo R., Cunha Neto, Álvaro, Rittner, Roberto, Bitencourt, Michelle, Freitas, Matheus P., Aquino, Nilton S.
Format:	Artikel
Sprache:	eng
Schlagworte:	anti-inflammatory compounds MIA-QSAR N-arylsulfamoyl derivatives
Online-Zugang:	Volltext
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