IDO1‐mediated Trp‐kynurenine‐AhR signal activation induces stemness and tumor dormancy in oral squamous cell carcinomas

The non‐proliferative residual tumor cells in cancer therapeutics are considered tumor‐repopulating cells (TRCs) and a major issue for tumor recurrences and distant metastases. TRCs are stem cell‐like cancer cells repopulating tumors and associating with immune‐mediated tumor dormancy. Cell cycle ar...

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Veröffentlicht in:	Oral science international 2022-01, Vol.19 (1), p.31-43
Hauptverfasser:	Anzai, Hiromasa, Yoshimoto, Shohei, Okamura, Kazuhiko, Hiraki, Akimitsu, Hashimoto, Shuichi
Format:	Artikel
Sprache:	eng
Schlagworte:	IDO1 LGR6 oral squamous cell carcinoma stemness tryptophan‐kynurenine‐AhR signaling
Online-Zugang:	Volltext
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