MAP kinases regulate unfertilized egg apoptosis and fertilization suppresses death via Ca 2+ signaling

The default fate for eggs from many species is death by apoptosis and thus, successful fertilization depends upon suppression of the maternal death program. Little is known about the molecular triggers which activate this process or how the fertilization signal suppresses the default maternal apopto...

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Veröffentlicht in:Molecular reproduction and development 2004-03, Vol.67 (3), p.366-383
Hauptverfasser: Sadler, Kirsten C., Yüce, Özlem, Hamaratoǧlu, Fisun, Vergé, Valérie, Peaucellier, Gérard, Picard, André
Format: Artikel
Sprache:eng
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