Gonadal dysfunction due to cis-platinum

Gonadal function was studied in 15 patients, 12 pubertal or postpubertal, and three prepubertal, who had been treated during childhood for nonmetastatic osteosarcoma of the long bones by chemotherapy regimens that included cis‐platinum and adriamycin. Of seven postpubertal female patients assessed (...

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Veröffentlicht in:	Medical and pediatric oncology 1989, Vol.17 (5-6), p.409-413
Hauptverfasser:	Wallace, W. H. B., Shalet, S. M., Crowne, E. C., Morris-Jones, P. H., Gattamaneni, H. R., Price, D. A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Antineoplastic Combined Chemotherapy Protocols - adverse effects Biological and medical sciences Bone Neoplasms - drug therapy chemotherapy Cisplatin - administration & dosage Cisplatin - adverse effects Dose-Response Relationship, Drug Drug toxicity and drugs side effects treatment Estradiol - blood Female fertility Follicle Stimulating Hormone - blood Genital Diseases, Female - chemically induced Genital Diseases, Male - chemically induced Humans Luteinizing Hormone - blood Male Medical sciences Menstrual Cycle - drug effects osteosarcoma Osteosarcoma - drug therapy Pharmacology. Drug treatments Semen - drug effects Testosterone - blood Toxicity: urogenital system
Online-Zugang:	Volltext
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