A multicenter randomized placebo-controlled clinical trial of pramipexole for Tourette's syndrome

Background: Dopamine agonists could theoretically normalize the suspected central dopamine hypersensitivity in Tourette's syndrome. Methods: There was a multicenter randomized, placebo‐controlled, double‐blind clinical trial of pramipexole given for 6 weeks in 63 children and adolescents with T...

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Veröffentlicht in:	Movement disorders 2012-05, Vol.27 (6), p.775-778
Hauptverfasser:	Kurlan, Roger, Crespi, Giovanna, Coffey, Barbara, Mueller-Vahl, Kirsten, Koval, Stephen, Wunderlich, Glen
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Benzothiazoles - therapeutic use Biological and medical sciences Child clinical trial dopamine agonist Dopamine Agonists - therapeutic use Double-Blind Method Female Humans Male Medical sciences Multiple sclerosis and variants. Guillain barré syndrome and other inflammatory polyneuropathies. Leukoencephalitis Neurology pramipexole Severity of Illness Index tics Tourette Syndrome - drug therapy Tourette's syndrome treatment Treatment Outcome treatment, clinical trial
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