Cellular immortality: A late event in the progression of human squamous cell carcinoma of the head and neck associated with p 53 alteration and a high frequency of allele loss

Many human tumors contain variant cells that, unlike their normal counterparts, possess indefinite proliferative potential in vitro. However, little is known of the relevance of these immortal cells to human carcinomas in vivo. To investigate immortality in a human tumor system, we established cultu...

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Veröffentlicht in:	Molecular carcinogenesis 1995-08, Vol.13 (4), p.254-265
Hauptverfasser:	Edington, Kirsten G., Loughran, Oonagh P., Berry, Isabella J., Parkinson, E. Kenneth
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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