JmjC‐domain containing histone demethylase 1B‐mediated p15 Ink4b suppression promotes the proliferation of leukemic progenitor cells through modulation of cell cycle progression in acute myeloid leukemia

The histone demethylase JHDM1B has been implicated in cell cycle regulation and tumorigenesis. In addition, it has been reported that JHDM1B is highly expressed in various human tumors, including leukemias. However, it is not clearly understood how JHDM1B contributes to acute myeloid leukemia (AML)...

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Veröffentlicht in:	Molecular carcinogenesis 2013-01, Vol.52 (1), p.57-69
Hauptverfasser:	Nakamura, Satoki, Tan, Lin, Nagata, Yasuyuki, Takemura, Tomonari, Asahina, Aya, Yokota, Daisuke, Yagyu, Tomohiro, Shibata, Kiyoshi, Fujisawa, Shinya, Ohnishi, Kazunori
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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