Polymorphism of XRCC1 and the frequency of mutation in codon 249 of the p 53 gene in hepatocellular carcinoma among guangxi population, China

In hepatocellular carcinoma (HCC), hotspot mutation in codon 249 of the p 53 gene has been associated with exposure to aflatoxin B1 (AFB1). While the polymorphism of DNA repair gene X‐ray repair cross‐complementary group 1 (XRCC1) Arg399Gln may be related with AFB1‐DNA adducts and gene mutations. Fi...

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Veröffentlicht in:	Molecular carcinogenesis 2008-04, Vol.47 (4), p.295-300
Hauptverfasser:	Long, Xi Dai, Ma, Yun, Huang, Hong Dong, Yao, Jin Guang, Qu, De Ying, Lu, Yun Long
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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