Synthesis of a New PHEMA/PEO Enzymatically Biodegradable Hydrogel

We report the synthesis of a new enzymatically degradable gel based on PHEMA and PEO crosslinking macromonomer. The crosslinker contains the tripeptide sequence Gly‐Gly‐Leu, which is a substrate for proteases such as subtilisin or chymotrypsin. The crosslinker was obtained by the coupling reaction o...

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Veröffentlicht in:	Macromolecular rapid communications. 2006-07, Vol.27 (13), p.1004-1008
Hauptverfasser:	Khelfallah, Nawel S., Decher, Gero, Mésini, Philippe J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Applied sciences biodegradable enzymatic degradation Exact sciences and technology hydrogels macromonomer Organic polymers PEO PHEMA Physicochemistry of polymers Properties and characterization Solution and gel properties
Online-Zugang:	Volltext
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